Androgen Regulation in Spermatogenesis to Increase Male Fertility

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dc.contributoren-US
dc.creatorHasbi, Hasbi; Universitas Hasanuddin
dc.creatorGustina, Sri; Universitas Sulawesi Barat
dc.date2018-03-03
dc.date.accessioned2018-06-04T07:49:05Z
dc.date.available2018-06-04T07:49:05Z
dc.descriptionMale fertility is affected by quantity and quality of sperm which controlled by androgens (testosterone and 5α-dihydrotestosterone) mediated by androgen receptors (AR). Androgen receptors belong to receptor group of steroid hormone and a group of ligand-activated nuclear receptor superfamily. This paper explains androgen hormone and its regulation in spermatogenesis to increase male fertility. Regulation of androgen hormone in spermatogenesis include initiation of spermatogenesis, proliferation and maturation of Sertoli cells, germ cell development, spermatogonia, meiosis, and spermiogenesis. The role of androgen hormone in regulation of spermatogenesis is influenced by AR, luteinizing hormone (LH), and follicle stimulating hormone (FSH) levels. Disruption of spermatogenesis will cause low male fertility. However, low concentrations of AR, LH and FSH could be enhanced by exogenous gonadotrophine releasing hormone (GnRH), LH, FSH, and testosterone to increase male fertility.en-US
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dc.identifierhttp://medpub.litbang.pertanian.go.id/index.php/wartazoa/article/view/1643
dc.identifier10.14334/wartazoa.v28i1.1643
dc.identifier.urihttps://repository.pertanian.go.id/handle/123456789/4552
dc.languageeng
dc.publisherIndonesian Center for Animal Research and Developmenten-US
dc.relationhttp://medpub.litbang.pertanian.go.id/index.php/wartazoa/article/view/1643/1547
dc.rightsCopyright (c) 2018 Hasbi Hasbi, Sri Gustinaen-US
dc.source2354-6832
dc.source0216-6461
dc.sourceWARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences; Vol 28, No 1 (2018): March 2018; 13-22en-US
dc.subjecten-US
dc.titleAndrogen Regulation in Spermatogenesis to Increase Male Fertilityen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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