Role of Natural Immunomodulator (Aloe Vera) in Cellular and Humoral Immune Responses

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dc.creatorWiedosari, Ening
dc.date2007-12-01
dc.date.accessioned2018-06-04T07:49:06Z
dc.date.available2018-06-04T07:49:06Z
dc.descriptionAloe vera belongs to a group of Liliaceae family plant and cultivated worldwide. It possesses acemannan (acetylated mannan), which has a significant pharmacological property. The acemannan has an immunomodulatory activity when administered to animals. The major immunomodulating effect includes the activation of immune effector cells, such as lymphocytes and macrophages, resulting in the production of cytokines, interleukin (IL)-1, IL-6, IL-12 and tumor necrosis factor alpha (TNFα). In particular, this extract can modulate the differentiation capacity of CD4+T cells to mature into Th1 subsets and enhance the innate cytokine response. As a consequence, this extract will have a profound effect in controlling disease, caused by intracellular infectious agents (bacteria and viruses). However, further studies are needed to determine the immunomodulating effects of Aloe vera in multi-component extracts equivalent to what are being  used commonly in traditional medicine.   Key words: Aloe vera, immunomodulator, cytokinesen-US
dc.formatapplication/pdf
dc.identifierhttp://medpub.litbang.pertanian.go.id/index.php/wartazoa/article/view/871
dc.identifier10.14334/wartazoa.v17i4.871
dc.identifier.urihttps://repository.pertanian.go.id/handle/123456789/4561
dc.languageeng
dc.publisherIndonesian Center for Animal Research and Developmenten-US
dc.relationhttp://medpub.litbang.pertanian.go.id/index.php/wartazoa/article/view/871/880
dc.source2354-6832
dc.source0216-6461
dc.sourceWARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences; Vol 17, No 4 (2007): DECEMBER 2007; 165-171en-US
dc.titleRole of Natural Immunomodulator (Aloe Vera) in Cellular and Humoral Immune Responsesen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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