Genetic characteristic of protein membran of avian influenza viruses H5N1 subtype

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dc.creatorDharmayanti, N.L.P Indi
dc.creatorHewajuli, D.A
dc.creatorRatnawati, A
dc.creatorIndriani, R
dc.creator., Darminto
dc.date2012-03-04
dc.date.accessioned2018-06-04T06:47:56Z
dc.date.available2018-06-04T06:47:56Z
dc.date.issued2012-03-04
dc.descriptionIn 2006-2008 there were findings about the antigenic drift on AI virus due to vaccination and the AI H5N1 subtype viruses which was similar to H5N1 viruses in human. The findings indicated that the AI viruses continue and undergoing to mutate and try to adapt with their environment.  The objective of this study was to characterize the mutation of recent AI viruses (2009) on the membran protein namely Hemagglutinin (HA), Neuraminidase (NA) and Matrix 2 (M2). In this study RT-PCR – sequencing methods and genetic analysis for the protein membran of AI viruses were used. Result revealed that there were specific mutation belong to AI 2009 viruses on HA and NA protein such as AI virus mutation in 2008 which was isolated from backyard chicken. The mutations were non synonimous and not caused by immunological pressure. Furthermore, M2 analysis indicated that the viruses were resistant to amantadine. Key Words: Mutation, AI Subtype H5N1 Viruses, Membran Proteinen-US
dc.formatapplication/pdf
dc.identifierhttp://medpub.litbang.pertanian.go.id/index.php/jitv/article/view/662
dc.identifier10.14334/jitv.v15i3.662
dc.identifier.urihttps://repository.pertanian.go.id/handle/123456789/3093
dc.languageeng
dc.publisherIndonesian Animal Sciences Societyen-US
dc.relationhttp://medpub.litbang.pertanian.go.id/index.php/jitv/article/view/662/671
dc.rightsCopyright (c) 1970 Indonesian Journal of Animal and Veterinary Sciencesen-US
dc.rightshttp://creativecommons.org/licenses/by/4.0en-US
dc.source2252-696X
dc.source0853-7380
dc.sourceIndonesian Journal of Animal and Veterinary Sciences; Vol 15, No 3 (2010): SEPTEMBER 2010; p.231-239en-US
dc.titleGenetic characteristic of protein membran of avian influenza viruses H5N1 subtypeen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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