Vaccination of Quails with Bivalent Inactivated H5N1 AI Vaccine (Clades 2.1.3 and 2.3.2) at Laboratory Scale

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dc.contributoren-US
dc.creatorIndriani, Risa; Indonesian Research Center for Veterinary Science
dc.creatorDharmayanti, NLP Indi; Indonesian Research Center for Veterinary Science
dc.date2017-03-31
dc.date.accessioned2018-06-04T07:56:32Z
dc.date.available2018-06-04T07:56:32Z
dc.descriptionQuails, Coturnix sp, are commercially bred for meat and egg production in order to support the needs for animal protein. Cases of H5N1 Avian Influenza still occur sporadically at quail farms. Vaccination become an option as a precaution against possible exposure to H5N1 AI virus. Thirty quails were vaccinated with bivalent inactivated H5N1 AI vaccine (clade 2.1.3 and 2.3.2) and 10 quails were used as control group. The quails were vaccinated with one dose (0.3 ml) per bird intramuscularly at the age of 23 days and booster was done at the age of 45 days. The response after a single vaccination showed that antibody titers were not optimal, but after the booster vaccination the antibody titers showed 4.2 log2 in average against the H5N1 AI antigen of clade 2.1.3 and 3.7 log2 against the antigen of clade 2.3.2. A challenge test with H5N1 influenza virus either with clade 2.1.3 or clade 2.3.2 indicated a 70% protection. Nevertheless, viral shedding was detected ≥7 days post-challenge. As conclusion, vaccination with inactivated bivalent vaccine H5N1 AI clades 2.1.3 and 2.3.2 induced antibody that were was not homogenous nor optimal.en-US
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dc.identifierhttp://medpub.litbang.pertanian.go.id/index.php/proceedings/article/view/1450
dc.identifier10.14334/Proc.Intsem.LPVT-2016-p.441-448
dc.identifier.urihttps://repository.pertanian.go.id/handle/123456789/4921
dc.languageeng
dc.publisherIndonesian Center for Animal Science Research and Development (ICARD)en-US
dc.relationhttp://medpub.litbang.pertanian.go.id/index.php/proceedings/article/view/1450/1386
dc.rightsCopyright (c) 2017 Proceeding International Seminar on Livestock Production and Veterinary Technologyen-US
dc.sourceProceedings of International Seminar on Livestock Production and Veterinary Technology; 2016; 441-448en-US
dc.subjectQuails; H5N1 AI Vaccine; Avian Influenzaen-US
dc.titleVaccination of Quails with Bivalent Inactivated H5N1 AI Vaccine (Clades 2.1.3 and 2.3.2) at Laboratory Scaleen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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