Spontaneous cholangiohepatitis in broiler chickens: immunohistochemical study of Ito cells

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dc.creator Handharyani, E
dc.creator Ochiai, K
dc.creator Winarsih, W
dc.creator Harlina, E
dc.creator Estuninngsih, Salfina Nurdin
dc.date 2014-02-17
dc.date.accessioned 2018-06-04T06:47:43Z
dc.date.available 2018-06-04T06:47:43Z
dc.date.issued 2014-02-17
dc.identifier http://medpub.litbang.pertanian.go.id/index.php/jitv/article/view/245
dc.identifier 10.14334/jitv.v6i4.245
dc.identifier.uri http://repository.pertanian.go.id/handle/123456789/2999
dc.description The function of Ito cells is expanding from a fat-storing site to a center of extracellular matrix metabolism and mediator production in the liver. Immunohistochemical reactivities of Ito cells were examined in eight livers of broiler chickens affected with spontaneous cholangiohepatitis and six chicken livers with malformation of extrahepatic biliary tracts. The livers in both groups revealed severe diffuse fibrosis. Ito cells expressing HHF35 muscle actin and desmin actively proliferated in the fibrotic foci of the all livers. The immunoreactivities of Ito cells to antibodies were enhanced compared with those in normal livers. There were no immunohistochemical differences between the Ito cells of two groups. From these findings, it was suggested that Ito cells actively proliferate and show enhanced immunoreactivities in the livers affected with cholangiohepatitis andmalformation of extrahepatic biliary tracts.   Key words : Cholangiohepatitis, immunohistochemistry, ito cell, broiler chicken en-US
dc.format application/pdf
dc.language eng
dc.publisher Indonesian Animal Sciences Society en-US
dc.relation http://medpub.litbang.pertanian.go.id/index.php/jitv/article/view/245/245
dc.rights Copyright (c) 1970 Indonesian Journal of Animal and Veterinary Sciences en-US
dc.rights http://creativecommons.org/licenses/by/4.0 en-US
dc.source 2252-696X
dc.source 0853-7380
dc.source Indonesian Journal of Animal and Veterinary Sciences; Vol 6, No 4 (2001): DECEMBER 2001; p.227-232 en-US
dc.title Spontaneous cholangiohepatitis in broiler chickens: immunohistochemical study of Ito cells en-US
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.type Peer-reviewed Article en-US


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