Immunohistochemical study of Ito cells of spontaneous cholangiohepatitis in broiler chickens

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dc.contributor en-US
dc.creator Handharyani, E
dc.creator Ochiai, K.
dc.creator Winarsih, W.
dc.creator Harlina, E.
dc.creator Estuninngsih, S. 2014-02-17 2018-06-04T06:47:08Z 2018-06-04T06:47:08Z 2014-02-17
dc.identifier 10.14334/jitv.v6i4.265
dc.description The function of Ito cells is expanding from a fat-storing site to a center of extracellular matrix metabolism and mediator production in the liver. Immunohistochemical reactivities of Ito cells were examined in eight livers of broiler chickens affected with spontaneous cholangiohepatitis and six chicken livers with malformation of extrahepatic biliary tracts. The livers in both groups revealed severe diffuse fibrosis. Ito cells expressing HHF35 muscle actin and desmin actively proliferated in the fibrotic foci of the all livers. The immunoreactivities of Ito cells to antibodies were enhanced compared with those in normal livers. There were no immunohistochemical differences between the Ito cells of two groups. From these findings, it was suggested that Ito cells actively proliferate and show enhanced immunoreactivities in the livers affected with cholangiohepatitis and malformation of extrahepatic biliary tracts.Key words: Cholangiohepatitis, immunohistochemistry, ito cell. broiler chicken en-US
dc.format application/pdf
dc.language eng
dc.publisher Indonesian Animal Sciences Society en-US
dc.rights Copyright (c) 1970 Indonesian Journal of Animal and Veterinary Sciences en-US
dc.rights en-US
dc.source 2252-696X
dc.source 0853-7380
dc.source Indonesian Journal of Animal and Veterinary Sciences; Vol 6, No 4 (2001): DECEMBER 2001; p.274-278 en-US
dc.title Immunohistochemical study of Ito cells of spontaneous cholangiohepatitis in broiler chickens en-US
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.type Peer-reviewed Article en-US

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